在CT成像中甲状腺密度作为COVID-19肺部参与的潜在标志物:回顾性分析
Suhasini Balasubramaniam1, Aparna Suresh Kumar2, Pravin Pandian1
1Radiodiagnosis, Government Stanley Medical College and Hospital, Chennai, IND.
Cureus
|June 6, 2024
概括
这项研究发现,CT扫描中的甲状腺密度与COVID-19患者的肺部参与之间没有显著的关联. 甲状腺密度不是SARS-CoV-2感染肺部疾病严重程度的可靠指标.
科学领域:
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
背景情况:
- SARS-CoV-2 流行病影响多个器官系统,包括内分泌系统.
- 新出现的证据表明COVID-19和甲状腺功能之间的相互作用,激素水平和腺体结构的潜在变化.
- 调查COVID-19患者的甲状腺变化对于了解系统性影响至关重要.
研究的目的:
- 探索CT成像中甲状腺密度与COVID-19诊断患者肺部参与之间的关联.
- 确定甲状腺密度是否可以作为SARS-CoV-2感染肺部疾病程度的预测标记.
主要方法:
- 对1066名接受非对比胸部CT扫描的COVID-19患者进行了回顾性横截面分析.
- 甲状腺密度和肺部参与的定量评估.
- 统计分析包括Kruskal-Wallis H测试和Shapiro-Wilk测试来分析相关性.
主要成果:
- 大多数患者 (70.3%) 的甲状腺密度正常.
- 改变的甲状腺密度和结节的甲状腺密度分别在19.9%和9.8%的患者中观察到.
- 在甲状腺密度类别和肺部参与程度之间没有发现统计学意义上的关联.
结论:
- 在CT成像中甲状腺密度似乎不是评估COVID-19患者肺部参与的可靠标记.
- 需要进一步的研究来阐明COVID-19和甲状腺功能之间的复杂关系.
- 了解这些相互作用可以为患者的管理和预后提供信息.
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