血清阴性粒状瘤与多炎与孤立的肺病变:一个病例报告
Harkesh Arora1, Dhiran Sivasubramanian2, Sinduja Sivakumar3
1Hospital Medicine, Lovelace Medical Center, Albuquerque, USA.
Cureus
|June 6, 2024
概括
这项案例研究突出了一个罕见的GPA (无ANCA抗体) 呈现的细粒体病例,具有孤立的肺病变. 通过活检证实了诊断,患者对rituximab治疗反应良好.
科学领域:
- 类风湿病学 类风湿病学
- 肺部病理学 肺部病理学
- 病理学 病理学 病理学
背景情况:
- 带有多炎 (GPA) 的颗粒瘤,一种死性血管炎,通常会影响中小血管,涉及呼吸道和脏.
- 诊断往往依赖于蛋白酶-3抗中性粒细胞体抗体 (PR3-ANCA) 的阳性,以及特征性颗粒瘤和质核突炎.
- 然而,不典型的表现,包括血清阴性病例,需要彻底的诊断评估.
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