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Updated: Jun 24, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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在帕金森病中使用循环素依赖性激酶5 (CDK5) 抑制剂

Mohammed Alrouji1, Haydar M Al-Kuraishy2, Ali I Al-Gareeb2

  • 1Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Shaqra, Saudi Arabia.

Journal of cellular and molecular medicine
|June 6, 2024
PubMed
概括

过度激活的环素依赖激酶5 (Cdk5) 有助于帕金森病 (PD) 神经退行. 包括他类药物和甲胺在内的Cdk5抑制剂在缓解PD进展和神经病理方面具有潜力.

关键词:
这是一种Cdk5抑制剂.帕金森病是帕金森病的一种疾病.循环林依赖性酶5的作用神经退行症的神经退行症

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