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Updated: Jun 24, 2025

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
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由结合部位调节的异构型SN-38前药物的超分子组合

Zhenhai Tang1, Jianhua Zhang1, Wenting Li1

  • 1College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China. hsu@scu.edu.cn.

Journal of materials chemistry. B
|June 6, 2024
PubMed
概括

这项研究使用SN38原药设计了超分子聚合物 (SPs). 在体内,20-OEG-SN38异构体表现出优异的抗瘤效果和稳定性,而不是10-OEG-SN38异构体和阴素.

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