孕产妇血糖控制不良会增加新生儿左心室缩的风险
Chayaporn Vasinchatchawal1, Somjate Suntratonpipat1, Chokchai Ruangroj2
1Department of Pediatrics, Phramongkutklao Hospital and Phramongkutklao College of Medicine, Bangkok, Thailand.
Minerva pediatrics
|June 6, 2024
概括
患有左心室缩 (LVH) 的糖尿病母亲 (IDMs) 的婴儿显著更有可能在妊娠年龄 (LGA) 中大,并且出生于血糖控制不佳的母亲. 这些因素是IDM中LVH的关键预测因素.
科学领域:
- 新生儿心脏病学 新生儿心脏病学
- 孕产妇和胎儿的医学
- 内分泌学 在内分泌学.
背景情况:
- 左心室缩 (LVH) 是糖尿病母亲 (IDM) 婴儿的重大并发症.
- 影响LVH发病率的因素,包括母亲的血糖控制和婴儿大小 (大于妊娠年龄 - LGA),需要进一步阐明.
- 这项研究调查了IDM中LVH的孕产妇和新生儿风险因素.
研究的目的:
- 为了确定糖尿病母亲 (IDM) 婴儿中LVH的患病率.
- 确定与IDMs中LVH发展相关的孕产妇和新生儿风险因素.
- 评估母亲血糖控制和婴儿LGA状态对LVH发病率的影响.
主要方法:
- 一项前性分析研究在三级护理医院进行了一年.
- 在出生后72小时内,先天性IDM被评估,使用2D心声学来识别心室缩.
- 收集和分析了关于母亲血糖控制和婴儿人类学数据.
主要成果:
- 在160名IDM中,LVH的患病率为20.6% (33名婴儿).
- 血糖控制较差的母亲所生婴儿的LVH发病率明显高 (45.5%vs14.4%).
- 对于妊娠年龄大 (LGA) 的婴儿显示LVH的患病率更高 (36.5%vs13.4%非LGA).
- 与没有LVH的人相比,患有LVH的IDM显著改变了左心室几何和质量.
结论:
- 新生儿心室缩影响20.6%的糖尿病母亲的婴儿.
- 孕产妇血糖控制不佳和婴儿的LGA状态被确定为该人群中LVH的主导风险因素.
- 这些发现强调了怀孕期间血糖管理和监测婴儿生长的重要性,以预防新生儿并发症.
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