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Updated: Jun 24, 2025

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巨细胞衍生FGFR1通过PLCγ介导的NF-κB炎症信号通路的激活驱动动动动脉硬化

Lintao Wang1,2,3, Wu Luo1,4, Suya Zhang3

  • 1Department of Pharmacy and Institute of Inflammation, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Shangtang Road 158, Hangzhou, Zhejiang 310014, China.

Cardiovascular research
|June 6, 2024
PubMed
概括

巨细胞中的纤维细胞生长因子受体1 (FGFR1) 通过驱动炎症和脂质吸收促进动脉样硬化. 抑制FGFR1可以减少动脉样硬化病变,这表明FGFR1是心血管疾病的治疗点.

关键词:
动脉样硬化是一种动脉样硬化.一个FGFR1.炎症 炎症是一种炎症.巨细胞是一个巨细胞.核因子-κBB 的核因子.氧化LDL是一种LDL.

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