门诊亲肠道抗菌药物治疗的当前实践和挑战:叙述性综述
Zenaw T Wolie1, Jason A Roberts1,2,3,4, Mark Gilchrist5,6
1UQ Centre for Clinical Research, Faculty of Medicine, University of Queensland, Brisbane, QLD 4029, Australia.
门诊亲肠道抗菌疗法 (OPAT) 为感染管理提供了延长住院治疗的替代方案. 本综述强调全球OPAT实践和挑战,强调需要优化以改善患者的治疗结果和降低医疗保健成本.
科学领域:
- 传染性疾病 传染性疾病
- 医疗保健管理的管理
- 药理学 药理学是指药理学的学科.
背景情况:
- 由于感染而延长住院的费用很高,并存在不良事件的风险.
- 越来越多的医疗需求和患者对家庭护理的偏好推动了家庭医院计划.
- 门诊亲肠道抗微生物治疗 (OPAT) 是这些计划的关键组成部分,涉及非医院环境中的IV抗微生物药物.
研究的目的:
- 在全球范围内审查当前的门诊亲肠道抗微生物治疗 (OPAT) 实践.
- 确定和描述与全球OPAT实施相关的挑战.
- 为优化OPAT服务的未来研究提供信息.
主要方法:
- 全球OPAT实践的系统审查.
- 分析患者选择标准和护理提供模式.
- 在OPAT中使用的常见抗菌剂的识别.
主要成果:
- 在不同地区,OPAT的实践有很大差异.
- 通常使用的抗微生物药物包括β-乳糖胺,氨基甘油酸,糖,诺基诺和乙甘.
- 关键的挑战包括设备并发症,副作用,监测,药物稳定性,患者遵守性和团队结构.
结论:
- 对特定感染而言,OPAT为住院护理提供了一个可行的替代方案.
- 解决管理,监测和患者参与方面的挑战对于OPAT成功至关重要.
- 需要进一步的研究来优化OPAT服务,以提高医疗保健效率和患者利益.
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