在西班牙裔和非西班牙裔成年人中,身体活动,心血管状况,死亡率和糖尿病前期
Sarah K Alver1, Stephanie Pan2, Yasmin Mossavar-Rahmani3
1Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, Washington.
JAMA network open
|June 6, 2024
概括
身体活动 (PA) 与正常血糖的成年人心血管疾病 (CVD) 和死亡风险较低有关,但在糖尿病前期患者中并非如此. 患有糖尿病前期的成年人可能从减少久坐行为和采用更广泛的生活方式改变中获益更多.
科学领域:
- 心血管健康 心血管健康
- 代谢障碍 代谢障碍 代谢障碍
- 公共卫生 公共卫生
背景情况:
- 关于糖尿病前期体力活动 (PA) 和心血管疾病 (CVD) 风险的数据有限,特别是在西班牙裔和拉丁裔人群中.
- 了解这些关联对于有针对性的公共卫生干预至关重要.
研究的目的:
- 检查PA与西班牙裔/拉丁裔和非西班牙裔成年人中发生心血管疾病或死亡率之间的关联,按糖尿病前期状况分层.
- 确定在不同人群中预防心血管疾病的最佳PA策略.
主要方法:
- 一项使用西班牙裔社区健康研究/拉丁裔研究 (HCHS/SOL) 和弗雷明翰心脏研究 (FHS) 数据的队列研究.
- 参与者 (n=13,223) 患有糖尿病前期或正常血糖症,在基线无心血管疾病,被跟踪查看发生心血管疾病或全因死亡率.
- 使用加速度计测量了中度至强度的PA,分析考虑了PA指南,每天的步骤和久坐行为.
主要成果:
- 较低的中度至强度的PA与患有正常血糖症的成年人心血管疾病或死亡风险较高有关 (HR,1.85;95% CI,1.12-3.06).
- 这种关联在糖尿病前期的成年人中没有统计学意义 (HR,1.07;95% CI,0.72-1.58).
- 在其他PA指标 (步骤,久坐行为) 与糖尿病前期组的复合结果之间没有发现显著的关联.
结论:
- 在美国成年人中,较低的体力活动水平与正常血糖症患者中心血管疾病或死亡风险增加有关,但不是糖尿病前期患者.
- 患有糖尿病前期的成年人可能会从不仅仅是增加中度至强度的血压增加的策略中获益更多,例如减少久坐时间和采用全面的生活方式修改.
- 需要进一步的研究来阐明针对糖尿病前期患者的特定PA建议.
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