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Updated: Jun 24, 2025

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
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Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase

Published on: April 29, 2010

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复制蛋白A在原料/模板连接处动态重组,允许DNA聚合酶 δ全酶组装并启动DNA合成

Jessica L Norris1, Lindsey O Rogers1, Kara G Pytko1

  • 1Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.

Nucleic acids research
|June 6, 2024
PubMed
概括

DNA聚合酶三角 (pol δ) 全酶协调DNA的合成和修复. 新的FRET测试显示,RPA在原料/模板连接处动态重组,使RFC和pol δ的顺序结合成为DNA复制启动.

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