虚拟群体认知刺激治疗痴呆症:混合方法可行性随机对照试验
Aimee Spector1, Nur Diyanah Abdul Wahab1, Joshua Stott1
1Department of Clinical, Health, and Educational Psychology, University College London, London, UK.
The Gerontologist
|June 6, 2024
概括
虚拟认知刺激疗法 (vCST) 对痴呆症患者是可行的,显示出高出席率和可接受性. 虽然这项可行性研究没有发现统计结果差异,但它证明了对vCST有效性的更大规模试验是合理的.
科学领域:
- 老年学是指老年学的学科.
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 认知刺激疗法 (CST) 是一种成熟的痴呆症小组干预,改善认知和生活质量.
- 卫生和交通等障碍限制了面对面的CST的访问.
- 虚拟交付CST (vCST) 为更广泛的可访问性提供了一个潜在的解决方案.
研究的目的:
- 评估提供认知刺激治疗 (CST) 虚拟 (vCST) 的可行性和可接受性.
- 评估vCST作为轻度至中度痴呆症患者的可访问干预措施的潜力.
主要方法:
- 一个单盲,随机控制的可行性试验.
- 46名患有轻度至中度痴呆症的参与者被随机分配到vCST (7周的14次会议) 或通常的治疗 (TAU).
- 通过出席,坚持,忠诚和招聘来评估可行性;通过定性面试来评估可接受性;通过前后评估来评估结果.
主要成果:
- 观察到高出席率,坚持和忠实于vCST手册.
- 招募是可行的,尽管随机化的可接受性有所不同.
- 在vCST和TAU组之间没有发现认知,生活质量或抑郁症的统计学上显著差异.
- 定性数据和参与者反表明了可接受性和潜在的益处.
结论:
- 虚拟认知刺激疗法 (vCST) 是痴呆症患者的一种可行的干预措施.
- 可行性试验支持需要一个更大的,全功率的随机对照试验 (RCT),以确认vCST的有效性.
- 在全球范围内,vCST是提供痴呆症干预措施的有希望的适应方案.
相关概念视频
Blind Procedures
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which child was...
Randomized Experiments
The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Simple randomization
Simple...


