急性COPD恶化和与住院治疗相关的问题:一项观察性研究
Oriana Awwad1, Rana Abu Farha2, Anood Altaharwah1
1Department of Biopharmaceutics and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Amman, Jordan.
PloS one
|June 6, 2024
概括
与治疗相关的问题 (TRPs) 在约旦住院的COPD恶化患者中很常见,不必要的药物治疗是主要问题. 解决这些TRP可以为医疗保健系统带来显著的成本节约和避免.
科学领域:
- 药物经济学 药物经济学
- 临床药房 临床药房
- 呼吸系统医学 呼吸系统医学
背景情况:
- 与治疗相关的问题 (TRPs) 对医疗保健系统构成重大负担,特别是对于急性病症住院患者.
- 对COPD急性恶化 (AECOPD) 患者的TRP数据有限,没有先前在约旦进行的研究.
- 这项研究通过对约旦AECOPD患者的TRP进行调查来弥补这一差距.
研究的目的:
- 在约旦的住院AECOPD患者中调查和分类TRPs.
- 估计与这些TRP相关的成本节约和成本避免.
- 为优化呼吸系统护理患者管理提供证据.
主要方法:
- 基于人口的回顾性队列研究设计.
- 从电子健康记录中使用AbuRuz工具识别和分类TRP (2017年1月-2021年7月).
- 使用已确定的方法 (Nesbit方法) 估计节省成本和避免成本.
主要成果:
- 在住院期间共确定了1243名TRP,并在出院时确定了503名TRP.
- "不必要的药物治疗"分别占TRP的49.4%和66.7%.
- 系统性皮质类固醇在54.5%的病例中被过度使用,估计节省了15745.7美元的成本,避免了340,455.5.5美元的成本.
结论:
- 在约旦的AECOPD患者中,TRP是普遍且昂贵的,需要有针对性的干预.
- 系统性皮质类固醇的过度使用和不必要的药物治疗是改善的关键领域.
- 将临床药剂师整合到呼吸护理部门可以优化患者管理并减少TRP负担.
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