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Updated: Jun 24, 2025

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
07:49

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods

Published on: July 17, 2019

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在KRAS突变癌症中定义KRAS和ERK依赖的转录组

Jeffrey A Klomp1,2, Jennifer E Klomp1, Clint A Stalnecker1,2

  • 1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Science (New York, N.Y.)
|June 6, 2024
PubMed
概括

虽然KRAS促使癌症生长,但其机制尚不清楚. 我们的研究显示ERK信号是KRAS突变癌症生长和针对性治疗的关键.

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