长期临床过程和治疗结果在隐形和露面的急性区域外视网膜病变
Janine Yang1, Da Meng1, Atitaya Apivatthakakul1
1Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.
Ocular immunology and inflammation
|June 6, 2024
概括
急性区域隐形外视网膜病变 (AZOOR) 患者通常保持视力敏度 (VA). 用类固醇治疗或免疫调节疗法 (IMT) 在明显的AZOOR病例中稳定了VA,一些患者显示视野有所改善.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 炎症性眼睛疾病 炎症性眼睛疾病
背景情况:
- 急性区域隐形外视网膜病变 (AZOOR) 是一种影响视网膜外侧的炎症状况.
- 了解AZOOR的纵向结果和治疗反应对于患者管理至关重要.
- 与其他白点综合征的重叠,如MEWDS,需要进一步调查.
研究的目的:
- 为了评估AZOOR患者的长期结果.
- 评估治疗反应,包括视力敏度的变化和 fundus 病变.
- 为了调查AZOOR患者多发 evanescent白点综合征 (MEWDS) 的发生情况.
主要方法:
- 视敏度 (VA) 和视野 (VF) 结果在隐形和明显AZOOR亚型中的回顾性比较.
- 对VA和底部损伤区域治疗效应的分析.
- 使用STATA 17进行统计分析.
主要成果:
- 分析了17只眼睛 (隐藏的AZOOR) 和45只眼睛 (公开的AZOOR).
- 在两组中观察到logMAR VA的最小下降 (隐藏:0.00016/月,公开:0.009/月).
- 隐性AZOOR患者表现出更好的VF结果 (p=0.04); 3/36患者患有MEWDS.
结论:
- 随着时间的推移,AZOOR患者通常会保持视力敏.
- 过度AZOOR患者更经常接受类固醇或IMT治疗.
- 在公开的AZOOR患者中,治疗与VA稳定有关.
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