腹腔过早跳动的Posttextrasystolic再极化变化与结构性心脏病相关,并表明预后影响
Xu-Miao Chen1, Yang Wu1, Jin Yu2
1Department of Cardiology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China, and Key Laboratory of Assisted Circulation, NHC, Guangzhou, China.
腹腔过早跳动 (VPBs) 的后外静脉复极变化与结构性心脏病 (SHD) 有关. 这些变化,特别是QTdv,可能有助于识别SHD并评估患者的预后.
科学领域:
- 心脏病学 心脏病学
- 电力生理学 电力生理学
- 心脏诊断 心脏诊断
背景情况:
- 心室过早跳动 (VPBs) 可以导致危及生命的心律失常,特别是在有结构性心脏病 (SHD) 的患者中.
- 准确识别危险的VPB及其与SHD的关联仍然是一个临床挑战.
研究的目的:
- 调查VPBs和SHD的后偏离变化之间的关系.
- 评估VPBs患者中这些复极变化的潜在预后价值.
主要方法:
- 对125名SHD患者和156名没有SHD患者的24小时霍尔特记录的分析.
- 在VPBs之后测量平均和最大的QT差值 (QTdv).
- 对T和U波的形态分析 (PT2,反转的T波,Pu变化).
主要成果:
- 与非SHD组相比,SHD组的平均和最大QTdv显著更长 (AUC分别为0.931和0.910).
- 特定的T和U波变化 (PT2,反向T波,Pu) 显示出高特异性,但用于识别SHD的敏感性较低.
- 较高的平均QTdv和积极的Pu变化与较大的左心大小,较差的心脏功能和增加的非持久性心室高心率运行相关.
结论:
- 在VPB中发生的Postextrasystolic再极化变化与SHD的存在相关.
- QTdv和特定的T/U波形态在对VPB和SHD患者的预后评估中具有潜在价值.
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