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Updated: Jun 24, 2025

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
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Published on: July 14, 2016

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使用向代谢学,肝蛋白学,脂学和分析线粒体功能的分析,解读底层的cystathionine beta-synthase缺陷同胞细胞尿症的病理生理机制

Tomas Majtan1, Thomas Olsen2, Jitka Sokolova3

  • 1Department of Pharmacology, University of Fribourg, Faculty of Science and Medicine, Fribourg, 1700, Switzerland.

Redox biology
|June 6, 2024
PubMed
概括

囊氨酸β-合成酶 (CBS) 缺陷的同型素尿症 (HCU) 破坏了硫氨基酸代谢. 在小鼠模型中,一种氨酸限制饮食 (MRD) 改善了代谢平衡,并减少了肝蛋白质组失调.

关键词:
囊氨酸β-合成酶的使用.人类性囊性尿症.代谢学 代谢学 代谢学限制 metionin 的限制.蛋白质组学是指蛋白质组学.

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