在肺癌患者中,支气管动脉栓塞后复发性血栓塞的预测因素
Clement Hanotin1, Raphael Salvayre2, Louis Lassalle3
1Department of Radiology, Hôpital Tenon - Assistance Publique - Hôpitaux de Paris, Paris, France.
在CT血管学上大规模的血和肺动脉损伤预测了肺癌患者在支气管动脉栓塞后的复发出血. 这一发现有助于管理严重的血栓塞并指导治疗决策.
科学领域:
- 干预性放射学 干预性放射学
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
背景情况:
- 肺癌患者的严重血栓塞形成了一个重大的临床挑战.
- 支气管动脉栓塞 (BAE) 是危及生命的血栓塞的主要治疗方法.
- 确定BAE后复发的预测因素对于优化患者管理至关重要.
研究的目的:
- 确定与BAE后的复发性血栓塞相关的临床,放射和血管学因素.
- 专注于进入ICU的肺癌和严重血栓塞患者.
主要方法:
- 对144名肺癌患者的回顾性分析,这些患者接受了 BAE 治疗严重的血 (2014-2022年).
- 在一个月内复发血栓塞患者和没有复发血栓塞患者之间的患者特征的比较.
- 评估人口统计,实验室值,临床过程和成像发现.
主要成果:
- 34.7%的患者在一个月内出现了复发性血栓塞; 58%的患者需要第二次栓塞.
- 大规模的血,更高的SAPS II分数,terlipressin使用,缩/化以及CT血管学上的肺动脉 (PA) 损伤与复发有关.
- 复发的独立预测因素是CT血管学上的大规模血和PA损伤.
结论:
- 在CT血管学上大规模的血和PA损伤是肺癌患者在BAE后复发血的显著独立预测因素.
- 这些发现可以帮助分层风险,并为血管理的治疗策略提供信息.
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