在暴露于有机酸盐后,大鼠尿液中的11种代谢物的量化

Michael A Leninsky1, Vladislav E Sobolev2, Margarita O Sokolova1

  • 1Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, Thorez 44, St. Petersburg, 194223, Russia.

PubMed
概括

研究人员开发了一种HPLC-MS/MS方法来检测大鼠尿液代谢物,以识别有机酸盐 (OP) 中毒生物标志物. 在OP模型中,代谢物水平发生了类似的变化,这表明了潜在的诊断指标.

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