相关实验视频
Updated: Jun 24, 2025

05:44
Ultrasonographic Evaluation of Breast Cancer-related Lymphedema
Published on: January 12, 2017
10.0K
乳腺癌,淋巴瘤或肉瘤癌患者的女性的身体组成和左心室性能之间的关系
Leila Mabudian1, Kerry Reding2, Ralph B D'Agostino3
1Division of Cardiology, VCU Pauley Heart Center, Virginia Commonwealth University (VCU), PO Box 980335, Richmond, VA, USA.
Cardio-oncology (London, England)
|June 6, 2024
概括
体重指数 (BMI) 升高和特定脂肪沉积与癌症治疗期间心脏功能降低有关. 需要进一步的研究来探索身体成分以外的其他贡献因素.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 在癌症治疗期间评估身体组成对心脏功能的影响.
- 调查高体重指数 (BMI),腹内脂肪组织 (IAT) 和皮下脂肪组织 (SAT) 与左心室喷射率 (LVEF) 变化之间的关系.
- 专注于为乳腺癌,淋巴瘤或肉瘤接受心脏毒性化疗的妇女.
研究的目的:
- 为了确定基线BMI,IAT和SAT与LVEF从基线到3个月的变化之间的关联.
- 了解身体组成如何影响接受化疗的癌症患者的左心室功能下降.
主要方法:
- 一项前性研究,涉及接受潜在心脏毒性化疗的女性.
- 磁共振成像 (MRI) 用于在基线和3个月的身体组成和心脏功能评估.
- 一般线性模型分析以检查脂肪组织储存,BMI和LVEF变化之间的关联.
主要成果:
- 基线BMI,IAT和SAT独立与3个月的LVEF下降相关 (p <0.025).
- 在调整心血管风险因素后,BMI仍然与LVEF下降显著相关 (p = 0.047).
- 最初的分析显示,脂肪储存和LVEF下降之间存在关联,但经过调整后,BMI是主要的预测因素.
结论:
- 除了IAT,SAT或传统的心血管风险因素之外的因素可能会影响接受化疗的女性的LVEF下降.
- 建议进行进一步的研究,以探索心理社会压力,体力活动,睡眠和饮食的作用.
相关概念视频
Imbalances in Cardiac Output
1.4K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.4K
Pathophysiology of Cardiac Performance
635
Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
635

