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Updated: Jun 24, 2025

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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Published on: July 25, 2020

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一个无的II/III期设计,用于瘤学药物开发的剂量优化

Yuhan Li1, Yiding Zhang2, Gu Mi2

  • 1Department of Statistics, University of Illinois Urbana-Champaign, Champaign, Illinois, USA.

Statistics in medicine
|June 7, 2024
PubMed
概括

这项研究引入了瘤药物试验的新无设计,在营销批准之前优化剂量. 这种方法提高了效率和灵活性,同时确保了可靠的剂量选择和统计能力.

关键词:
剂量优化剂量优化瘤学 在瘤学方面.这个项目是Optimus Optimus.再估计样本大小的重新估计.无设计 无设计

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