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Updated: May 5, 2026

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单细胞景观揭示了骨髓参与外围T细胞淋巴瘤的免疫异质性

Jun Liu1,2, Baijing Xia1,3, Xinmiao Jiang4

  • 1Medical Research institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.

Cancer science
|June 7, 2024
PubMed
概括

在外周T细胞淋巴瘤 (PTCL) 中,单细胞骨髓测序揭示了与预后相关的血管免疫细胞T细胞淋巴瘤 (AITL) 的免疫差异. 特定的T细胞子集和遗传突变会影响患者的治疗结果.

关键词:
血管免疫芽细胞T细胞淋巴瘤遗传变异是一种遗传变异.免疫异质性的异质性周围T细胞淋巴瘤一个单细胞RNA测序.瘤微环境是一个微环境.

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Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...
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