对治疗结核病相关呼吸系统残疾的干预措施进行范围审查
Cassandra Mbanje1, Isla Kuhn2, Nozipho Musakwa1
1Health Economics and Epidemiology Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
EClinicalMedicine
|June 7, 2024
概括
肺结核 (TB) 幸存者经常面临持久的呼吸系统问题,但综合护理指南尚不存在. 需要更多的研究来改善结核病患者的长期肺部健康.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 在肺结核 (TB) 患者和幸存者中,呼吸道疾病的高负担.
- 在治疗后,多达50%的患者会出现残留的呼吸道症状,异常的螺旋计或结构性病理.
- 对患者的生活和生计产生重大影响.
研究的目的:
- 审查对治疗结核病相关呼吸系统障碍的干预措施的现有证据.
- 识别有关临床疗效,成本效益和干预措施可行性的初级数据中的差距.
- 为开发综合性结核病呼吸系统护理框架提供信息.
主要方法:
- 范围审查与世卫组织全球结核病计划合作进行.
- 确定了预防和管理结核病相关呼吸系统损伤的潜在干预措施.
- 专注于确定有关干预有效性和实施的初级数据.
主要成果:
- 缺乏关于六种潜在干预措施的临床疗效,成本效益和可行性的初级数据.
- 没有针对儿童和青少年的研究.
- 没有现有的指导方针或基于证据的框架,用于综合结核病呼吸系统护理.
结论:
- 需要进行强大的干预试验,以改善肺结核患者的长期呼吸道结果.
- 迫切需要在资源有限的环境中探索这些干预措施的实施策略.
- 解决结核病相关的呼吸系统障碍对于患者的康复和福祉至关重要.
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