消化管胃肠道瘤的内镜切除:一个多中心可行性研究
Jingjing Lian1, Yingjie Ji1, Tao Chen1
1Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University, Shanghai, China.
Therapeutic advances in gastroenterology
|June 7, 2024
概括
内镜切除 (ER) 是对食道胃肠道瘤 (E-GISTs) 的可行的治疗方法,长度高达4厘米. 这项研究发现ER对E-GIST安全有效,在术后没有观察到复发.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 内镜手术 进行内镜手术
背景情况:
- 消化管胃肠道 stromal 瘤 (E-GISTs) 是罕见的和研究不足的.
- 关于对E-GISTs进行内镜切除的疗效的数据有限.
研究的目的:
- 评估内镜切除 (ER) 对E-GISTs的可行性和临床影响.
- 评估ER在治疗E-GIST中的安全性和有效性.
主要方法:
- 多中心回顾性研究包括23名患有E-GISTs的患者.
- 收集了临床病理学,内镜和随访参数的数据.
- 用内镜切除方法治疗的瘤的分析.
主要成果:
- 内镜切除 (ER) 在所有23名患者中实现了完全的瘤切除.
- 平均瘤大小为2.3厘米;较大的瘤 (>2厘米) 显示出更深的生长 (p<0.001).
- 没有需要手术的内科并发症,内镜治疗的出血最小;在随访期间没有复发或转移.
结论:
- 肠镜切除 (ER) 对于食道GIST≤4cm似乎是可行的和有效的.
- 建议进行粘膜下道内镜切除,因为瘤位于肌肉本身.
- 瘤大小大于2厘米与更深或外延伸的风险增加有关.
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