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Updated: Jun 24, 2025

The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice
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双特异性Sigma1R-对手/MOR-对手化合物治疗疼痛

Robert B Raffa1, Joseph V Pergolizzi2

  • 1Pharmacology, Temple University, Philadelphia, USA.

Cureus
|June 7, 2024
PubMed
概括

具有高度选择性的西格玛-1受体 (S1R) 和西格玛-2受体 (S2R) 配体澄清了受体功能. 针对S1R和mu-opioid受体的新双特异性化合物在疼痛管理方面表现有前途.

关键词:
止痛药是一种止痛药.两种特定的受体亲缘关系.穆阿片类受体 (mor) 的使用s1r子类型 s1r子类型西格玛受体的受体

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