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蒂皮法尼布可以减少细胞外囊泡,并保护心脏衰竭

Vandana Mallaredy1, Rajika Roy2, Zhongjian Cheng1

  • 1Aging and Cardiovascular Discovery Center (V.M., Z.C., C.T., C.B., M.T., D.J., A.M., J.I., M.C., C.G., V.N.S.G., R.K.), Lewis Katz School of Medicine, Temple University, Philadelphia, PA.

Circulation research
|June 7, 2024
PubMed
概括

在心力衰竭中,外体细胞会恶化心脏功能障碍和纤维化. 用蒂帕尼布抑制外体生物发生能改善心脏功能,通过恢复miR 331-5p水平来减少纤维化.

关键词:
细胞通信的细胞通信.纤维化 纤维化心脏衰竭是因为心脏衰竭.腹腔的重塑 腹腔的重塑

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