双核外结构材料的设计用于提取非类固醇抗炎药物
Hongmei Liu1, Shihao Dang1, Baogui Ye1
1School of Chemistry and Chemical Engineering, Lanzhou Jiaotong University, Lanzhou, China.
Journal of separation science
|June 7, 2024
概括
一种新的双核外材料,ZIFs@ZnS@CoS,增强了非类固醇抗炎药物 (NSAID) 的固相提取. 这种先进的材料为环境水样分析提供了卓越的提取效率和寿命.
科学领域:
- 材料科学 材料科学 材料科学
- 分析化学 分析化学
- 环境科学 环境科学
背景情况:
- 非类固醇抗炎药物 (NSAIDs) 是常见的环境污染物.
- 现有的固相提取 (SPE) 材料在效率和寿命方面存在局限性.
- 泽奥利特胺醇框架 (ZIFs) 是有前途的,但需要进行结构修改以提高性能.
研究的目的:
- 设计和合成一种新的双核外材料,用于增强NSAID的SPE.
- 评估新材料的提取效率,回收率和检测极限.
- 为了证明材料在真实环境水样中分析NSAID的适用性.
主要方法:
- 通过ZIF-8@ZIF-67.7.的衍生合成一个双核外材料 (CoS/ZIF-67/ZnS/ZIF-8).
- 合成材料在SPE中用于NSAID提取的应用.
- 使用高性能液态染色学 (HPLC) 来分析提取的NSAID.
- 分析方法的验证,包括恢复,检测极限和线性范围.
主要成果:
- 与ZIF-8@ZIF-67和ZIF-8相比,ZIFs@ZnS@CoS材料的提取效率更高,使用寿命更长.
- 开发的分析方法实现了高回收率 (98.93%-102.10%) 和低检测极限 (0.11-0.27μg/L).
- 该方法证明了广泛的线性范围 (1-200μg/L),具有很好的相关系数 (R2 = 0.9978-0.9993).
- 从黄河水样中成功提取NSAIDs.
结论:
- 设计的双核心外ZIFs@ZnS@CoS材料有效地利用其独特的结构,实现卓越的提取性能.
- 这种材料代表了NSAIDs在环境监测中的SPE的有希望的进步.
- 开发的分析方法是可靠的,适合在复杂矩阵中定量确定NSAIDs.
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