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Updated: Jun 24, 2025

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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针对性蛋白质降解系统,以增强Wnt信号传递

Parthasarathy Sampathkumar1, Heekyung Jung1, Hui Chen1

  • 1Surrozen, Inc, South San Francisco, United States.

eLife
|June 7, 2024
PubMed
概括

针对亚亚糖蛋白受体 (ASGR) 的新抗体增强了Wnt信号传递,并促进了向蛋白降解 (TPD). 这些工程分子为潜在的肝病治疗提供了联合治疗效果.

关键词:
在ASGR1中,它是ASGR1.在LYTAC中,我们可以使用LYTAC这就是PROTAC.在R-spondin的使用中.甜蜜的东西 甜蜜的东西他们不想做.生物化学 生物化学化学生物学 化学生物学没有,没有,没有.再生医学是一种再生医学.干细胞是干细胞的组成部分.

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