在丹麦首次COVID-19浪潮期间,分娩时的抗体状况和妊娠结果
Victoria Holten Springborg1, Julie Milbak1, Sissil Egge1
1Department of Obstetrics and Gynaecology, Copenhagen University Hospital - North Zealand, Hilleroed.
Danish medical journal
|June 7, 2024
概括
丹麦首次COVID-19浪潮显示,孕妇的SARS-CoV-2感染率较低. 母亲的抗体转移到新生儿身上,但没有影响怀孕的结果,尽管嗅觉丧失表明感染.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 随着COVID-19的流行,孕妇群体面临着独特的挑战.
- 了解SARS-CoV-2 (严重急性呼吸系统综合征冠状病毒2) 在怀孕期间的患病率和影响至关重要.
研究的目的:
- 为了确定在丹麦最初的COVID-19浪潮期间,孕妇和新生儿的SARS-CoV-2感染和抗体的流行率.
- 探索SARS-CoV-2抗体与母亲的特征,症状和怀孕结果之间的关联.
主要方法:
- 丹麦的一项前性队列研究包括953名活产妇.
- 数据收集涉及鼻抽样,血液样本 (母体和带),问卷和医疗记录.
主要成果:
- 在1.3%的女性中检测到SARS-CoV-2抗体,所有阳性母婴的新生儿也具有抗体.
- 嗅觉丧失与血清阳性有显著的相关性 (p < 0.001).
- 没有任何不良妊娠结果与母亲的SARS-CoV-2抗体相关.
结论:
- 在第一波期间,怀孕中COVID-19的流行率很低.
- 母亲的SARS-CoV-2抗体与带血抗体和嗅觉丧失有关,但没有不良结果.
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