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Updated: Jul 1, 2026

Live Imaging of Innate Immune and Preneoplastic Cell Interactions Using an Inducible Gal4/UAS Expression System in Larval Zebrafish Skin
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在斑马鱼中,IRAK3和IRAK1都激活了MyD88-TRAF6通路

Panwei Weng1,2, Mengjiao Lan1, Hao Zhang1

  • 1State Key Laboratory of Biocontrol, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-sen University, Guangdong, China.

Journal of immunology (Baltimore, Md. : 1950)
|June 7, 2024
PubMed
概括

斑马鱼IRAK1和IRAK4可以增强TLR/IL-1R信号通路. 确定了两种IRAK3变体:IRAK3a增强了轻微的信号传输,而IRAK3b抑制了它,为鱼类IRAK演变提供了新的见解.

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