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Updated: Jun 24, 2025

Identification of Kinesin-1 Cargos Using Fluorescence Microscopy
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在Myc Box I中的Missense突变影响核细胞质运输促进白血病发生

Nancy B J Arthur1, Keegan A Christensen1, Kathleen Mannino1

  • 1Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri.

Clinical cancer research : an official journal of the American Association for Cancer Research
|June 7, 2024
PubMed
概括

在急性髓性白血病 (AML) 中的MYC盒子I (MBI) 突变通过改变RNA运输促进癌症. 这些突变减少了细胞死亡,并加速了造血细胞中的瘤形成.

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