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为在临床试验中接触社会经济弱势群体绘制策略

Maria I Florez1, Emily Botto1, Jennifer Y Kim1

  • 1Tufts Center for the Study of Drug Development, Tufts University School of Medicine, Boston, Massachusetts.

JAMA network open
|June 7, 2024
PubMed
概括

营利性临床研究站点比非营利性站点使用更多的策略来招募社会经济弱势患者. 然而,大多数网站收集的社会经济数据很少,这凸显了在临床试验中改善患者多样性的需要.

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Strategies for Assessing and Addressing Confounding

Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
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Longitudinal Research

Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
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