相关实验视频
Updated: Jun 24, 2025

Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
患有功能性胃肠道疾病的高风险患者中患有乳病的患病率和相关因素
Ari Fahrial Syam1, Amanda Pitarini Utari1, Nur Hamidah Hasanah1
1Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
印度尼西亚成年人中乳病 (CD) 的患病率为2.83%. 在这种高风险人群中,自身免疫性疾病的病史是与CD相关的主要因素.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
- 流行病学 流行病学
背景情况:
- 乳病 (CD) 是一种自身免疫性小肠疾病,在遗传敏感的个体中由质触发.
- 全球CD患病率有所上升,但尽管谷蛋白摄入量增加,但对高风险的印尼成年人数据很少.
- 了解印尼的CD患病率和相关因素对于公共卫生至关重要.
研究的目的:
- 确定印尼高风险成年患者中乳病的患病率.
- 为了确定与印尼CD相关的临床迹象,症状,病史和生活方式因素.
- 调查印尼人口中CD和其他健康状况之间的关系.
主要方法:
- 一项观察性,横截面研究,涉及283名来自Cipto Mangunkusumo总医院的高风险成年患者.
- 数据收集包括通过ELISA问卷,人体测量和血清学测试 (IgA抗组织转质胺酶和IgG抗脱氨基蛋白).
- 统计分析采用了基平方和多变量逻辑回归 (SPSS v.26),p值<0.05被认为是显著的.
主要成果:
- 在283名患者中,有8名患者 (2.83%) 血清学证实患有乳病.
- 双变量分析显示了与年龄,便秘和自身免疫性疾病史 (p <0.05) 的显著关联.
- 多变量分析确定了自身免疫性疾病史作为唯一与CD相关的显著独立因素 (p <0.05).
结论:
- 在研究医院的高风险功能性胃肠道疾病患者中,乳病的患病率为2.83%.
- 年龄,便秘和自身免疫性疾病史被确定为与CD相关的潜在因素.
- 自身免疫性疾病的病史在这个印度尼西亚队列中成为与腹腔疾病相关的最重要的独立变量.
更多相关视频
10:27Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
06:01Author Spotlight: Reliable and Reproducible In Vitro Assessment of Drug Impact on Rat Intestinal Tubes
Published on: July 26, 2024
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Other Disorders of Digestive System
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Assessment of the Gastrointestinal System II: Health Perception Pattern
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...