截止点CT值可以识别死后CT上部胃肠道出血:开发和验证研究
Naomasa Okimoto1, Masanori Ishida1, Wataru Gonoi1
1Department of Radiology, Graduate School of Medicine, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo, Japan.
PloS one
|June 7, 2024
概括
尸检CT扫描可以使用特定的Hounsfield单位 (HU) 切断来诊断上部胃肠道出血 (UGIB). 值≥27.7HU,加上固体胃肠道含量,为UGIB提供了有效和可重复的诊断标准.
科学领域:
- 法医放射学 法医放射学
- 医疗成像医学成像
- 胃肠病学 胃肠病学
背景情况:
- 在死后检查中确定上部胃肠道出血 (UGIB) 的准确诊断标准至关重要.
- 尸体后计算机断层扫描 (PMCT) 提供了一种非侵入性方法来评估内部损伤和条件.
研究的目的:
- 用非对比的PMCT来确定UGIB的可靠诊断标准.
- 在单独的患者队列中验证这些标准.
主要方法:
- 一个病例控制研究,涉及有和没有尸检证明的UGIB的患者.
- 患者接受了非对比的PMCT和常规尸检.
- 图像检测结果,包括胃肠上部内容的CT值,在导出和验证组中进行了分析.
主要成果:
- 诊断UGIB的最佳切断CT值是≥27.7的Hounsfield单位 (HU),在导出和验证组中都有高灵敏度和特异性.
- 在UGIB病例中观察到的平均CT值为48.2HU,而非UGIB病例中为22.8HU.
- 将CT截止值与固体胃肠道含量发现相结合,在验证集中提高了特异性,但降低了灵敏度.
结论:
- 没有对比度的PMCT切线CT值≥27.7HU是诊断UGIB的有效和可重复的标准.
- 固体胃肠道内容的存在进一步提高了PMCT在诊断UGIB时的特异性.
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