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Updated: Jun 24, 2025

High Throughput In Vitro Assessment of Latency Reversing Agents on HIV Transcription and Splicing
07:18

High Throughput In Vitro Assessment of Latency Reversing Agents on HIV Transcription and Splicing

Published on: January 22, 2019

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组织素甲基转移酶SETD2调节HIV的表达和潜伏时间

Cameron R Bussey-Sutton1, Airlie Ward2,3, Joshua A Fox2,3

  • 1Department of Biochemistry, UNC Chapel Hill, Chapel Hill, North Carolina, United States of America.

PLoS pathogens
|June 7, 2024
PubMed
概括

抑制SETD2,沉积H3K36三甲基化 (H3K36me3),影响人类免疫缺陷病毒 (HIV) 的整合和表达. 这种表观遗传修饰影响病毒延迟和重新激活,为艾滋病毒治愈策略提供了新的目标.

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Epigenetic Regulation

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X-chromosome...
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