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Updated: Jun 24, 2025

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兄弟双胞胎在工作中:PLD3/4的结构揭示了 lysosomal核酸分解机制

Oliver Daumke1, Markus Damme2

  • 1Structural Biology, Max Delbrück Center for Molecular Medicine (MDC), 13125 Berlin, Germany; Institute for Chemistry and Biochemistry, Freie Universität Berlin, 14195 Berlin, Germany.

Structure (London, England : 1993)
|June 7, 2024
PubMed
概括

在结构上分析了 lysosomal phospholipase D (PLD) 蛋白质,PLD3和PLD4. 研究结果揭示了它们的DNA降解机制以及突变如何损害功能.

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