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Updated: Jun 24, 2025

Author Spotlight: A Selective Luciferase-Based Assay for Monitoring ATG4B 27 Activity in Cells
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自控制中的GPCR功能:化学干预的系统方法

Pablo Sanz-Martinez1, Georg Tascher2, Sara Cano-Franco1

  • 1Institute of Biochemistry II (IBC2), Faculty of Medicine, Goethe University, Frankfurt am Main, Germany; Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University, Frankfurt am Main, Germany.

Journal of molecular biology
|June 7, 2024
PubMed
概括

研究人员选了77个G蛋白结合受体 (GPCR) 配体,以了解自调节. 几种化合物调节了一般的自流量,其中一种特别增强了ER-phagy,揭示了GPCR信号传递.

关键词:
在G蛋白结合受体GPCRR中.基于TMT的全细胞蛋白质组学化学屏幕的使用方法化学遗传学图书馆 化学遗传学图书馆诱导自细胞的发生.信号传导的信号传导.

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