盆腔放射治疗后的移植:增加患病率?
Marc Françot1, Benoit Mesnard1, Clarisse Kerleau2
1Department of Urology, Nantes University Hospital, Nantes, France.
The French journal of urology
|June 7, 2024
概括
盆腔照射后的移植具有增加的外科复杂性,但仍然是安全的. 这种病史不应阻止患者接受移植,因为移植和患者的存活率不受影响.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术瘤学手术瘤学
背景情况:
- 盆腔辐射对移植手术的影响还不清楚.
- 评估移植后盆腔放射治疗的可行性和安全性至关重要.
研究的目的:
- 评估移植在有骨盆辐射病史的患者中的可行性和安全性.
- 为了比较受照射和非照射脏移植接受者的手术结果,并发症和生存率.
主要方法:
- 对从2005年至2021年之前接受骨盆辐射的患者的脏移植数据的回顾性分析.
- 匹配的队列研究比较照射患者与未照射的对照组.
- 收集了关于手术内参数,术后并发症,移植和患者存活率的数据.
主要成果:
- 在手术困难 (P<0.01),手术持续时间 (190分 vs. 149分钟,P=0.005) 和淋巴细胞发生 (P=0.041) 中观察到显著差异.
- 尿道解剖技术的变化被注意到,照射患者更频繁地接受尿道-尿道解剖 (29%) 与尿道-膀解剖 (58.3%) 相比.
- 在其他外科手术后的标准或生存率之间没有显著的差异.
结论:
- 盆腔辐射增加了移植的技术复杂性.
- 移植的安全性和移植的存活率不会受到盆腔辐射病史的影响.
- 患有盆腔辐射病史不应被视为移植的禁忌.
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