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水凝在免疫治疗中的最新进展:治疗乳腺癌

Jagannath Mondal¹, Kushal Chakraborty², Edwin J Bunggulawa³

¹4D Convergence Technology Institute, Korea National University of Transportation, Jeungpyeong 27909, Republic of Korea; Department of Green Bioengineering, Korea National University of Transportation, Chungju 27470, Republic of Korea; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA.

Journal of controlled release : official journal of the Controlled Release Society

|June 7, 2024

概括

水凝为乳腺癌免疫疗法提供了一种有前途的方法,通过调节瘤微环境并使向药物输送成为可能. 本综述探讨了它们对更有效,更为患者友好的乳腺癌治疗的潜力.

科学领域:

生物材料科学生物材料科学
癌症免疫疗法癌症免疫疗法
药物输送系统药物输送系统

背景情况:

乳腺癌是女性癌症相关死亡的主要原因.
传统治疗有局限性;免疫疗法提供了一个有针对性的,不那么有毒的替代方案.
水凝在临床前和临床环境中对乳腺癌治疗有希望.

研究的目的:

审查水凝在乳腺癌免疫治疗中的优势和机制.
为了突出最近的进展和水凝的刺激反应性质.
讨论基于水凝的治疗方法的治疗后考虑和临床转化.

主要方法:

在乳腺癌免疫治疗中对水凝应用的文献综述.
分析水凝的特性,包括瘤微环境调节和药物输送.
检查临床翻译和未来的前景.

主要成果:

水凝可以改变瘤的微环境,调节免疫反应.
它们有助于治疗剂的有针对性和持续释放.
最近的进展显示了临床前和临床研究的巨大潜力.

结论:

水凝代表了一种多功能平台,用于增强乳腺癌免疫疗法.
它们的整合可以导致更个性化,更有效,更为患者友好的治疗方法.
进一步的研究和临床翻译对于实现它们的全部潜力至关重要.

关键词:

乳腺癌乳腺癌乳腺癌组合疗法是一种联合疗法.水凝是一种水凝.免疫治疗是一种免疫疗法.手术后的治疗方法瘤微环境是一个微环境.

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