相关实验视频

Updated: Jun 24, 2025

CRISPR Epigenome Editing in Human Cells using Plasmid DNA Transfection and mRNA Nucleofection Delivery
07:49

CRISPR Epigenome Editing in Human Cells using Plasmid DNA Transfection and mRNA Nucleofection Delivery

Published on: May 30, 2025

823

一种基于CRISPR/dCas9的可编程表观遗传编辑系统,可实现定位向的素和精确的转录调节

Xiaoya Zhang1, Abhisek Bhattacharya2, Chunxiang Pu3

  • 1National Technology Innovation Center of Synthetic Biology, Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China; School of Pharmacy, Jilin University, Changchun, Jilin 130012, China.

Journal of genetics and genomics = Yi chuan xue bao
|June 7, 2024
PubMed
概括

研究人员开发了一种新型的表观遗传编辑器,以精确控制基因组素化,这是一个关键的表观遗传修饰. 这种工具可以通过操纵特定基因组位点的基因组素化来实现向基因调节.

关键词:
引定律化 引定律化表观遗传编辑器编辑器基因组合物 基因组合物乙烯氨基氨酸减小酶.dCas9 的使用情况

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