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Updated: Jun 24, 2025

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患有VACTERL儿童的生殖器形 - 是时候将"G"纳入缩写了吗?
Mette Hambraeus1, Anna Börjesson1, Ann Nozohoor Ekmark1
1Institution of Clinical Sciences, Lund University, Department of Pediatric Surgery, Skane University Hospital Lund, 221 85 Lund, Sweden.
Journal of pediatric surgery
|June 7, 2024
概括
生殖器形在患有VACTERL综合征的儿童中更为常见. 早期的生殖器评估对于这些患者来说至关重要,以防止长期的生殖健康问题.
科学领域:
- 儿科手术 儿科手术
- 医学遗传学 医学遗传学
- 生殖医学 生殖医学
背景情况:
- 生殖器形在VACTERL综合征中很常见,但没有得到正式承认.
- 食道缩 (EA) 和直肠形 (ARM) 是VACTERL.的关键特征.
研究的目的:
- 确定EA和/或ARM患者生殖器异常的频率.
- 分析VACTERL患者与非VACTERL患者的生殖器形率.
主要方法:
- 对前性收集的注册表 (2012-2022) 的回顾性分析.
- 包括为ARM和EA进行手术的患者.
- 针对VACTERL组件特征进行常规选.
主要成果:
- 在38%的VACTERL患者和11%的非VACTERL患者中发生了生殖器官形 (p < 0.001).
- 在VACTERL男孩中未下降的丸是常见的 (21%);在VACTERL女孩中Müllerian管道异常 (26%).
- 生殖器形频率与VACTERL组件特征的数量相关.
结论:
- 在VACTERL患者中生殖器形的发病率较高,强调需要进行彻底的生殖器评估.
- 建议VACTERL-G (生殖器) 改进诊断和减少长期生殖疾病.
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