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Updated: Jun 24, 2025

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
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在哺乳动物中探索植物衍生的植物色合伴蛋白用于光可切换的转录调节

Deqiang Kong1, Yang Zhou1,2, Yu Wei1

  • 1Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Biomedical Synthetic Biology Research Center, Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Dongchuan Road 500, Shanghai, 200241, China.

Nature communications
|June 7, 2024
PubMed
概括

植物衍生植物色素蛋白FHY1和FHL形成一个可切换光的复合体,用于精确的基因控制. 这种光传感转录调节复合体 (PTRC) 能够在哺乳动物细胞和小鼠中实现可调节的基因表达.

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