口服器械治疗与定位治疗用于管理定位阻塞性睡眠呼吸暂停;随机对照试验的系统审查和元分析
Abdelrahman Ma Mohamed1,2, Omar Magdy Mohammed3, Shanshan Liu4
1Department of Orthodontics, 1st Affiliated Hospital, Zhengzhou University, Zhengzhou, China. Abdelrahman@dent.suez.edu.eg.
BMC oral health
|June 7, 2024
概括
口服器械疗法 (OAT) 和姿势疗法 (PT) 都用于治疗阻塞性睡眠呼吸暂停. OAT表现出更大的有效性,在非仰卧姿势中显著降低了呼吸暂停-呼吸暂停指数,并改善了爱普沃思睡眠度量表的得分.
科学领域:
- 睡眠医学 睡眠医学
- 呼吸系统医学 呼吸系统医学
- 医疗器械 医疗器械
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种常见的睡眠障碍.
- 位置性阻塞性睡眠呼吸暂停是受睡眠姿势影响的亚型.
- 有效的管理策略对于患者的治疗结果至关重要.
研究的目的:
- 为了比较定位疗法 (PT) 和口服器械疗法 (OAT) 治疗定位阻塞性睡眠呼吸暂停的疗效.
- 评估PT和OAT之间的关键睡眠指标和患者报告的结果.
主要方法:
- 在PubMed,科学网络,Cochrane和SCOPUS中进行系统的文献搜索.
- 使用Cochrane偏差风险工具对临床试验的质量评估.
- 包括诸如呼吸暂停-呼吸暂停指数 (AHI),睡眠效率,坚持和爱普沃思睡眠度量 (ESS) 等结果.
主要成果:
- 与定位治疗 (PT) 相比,口服器械疗法 (OAT) 的非卧床AHI和爱普沃思睡眠度量 (ESS) 评分明显较低.
- 与OAT相比,PT与卧卧睡眠的百分比显著下降有关.
- 在OAT和PT之间没有观察到总AHI,卧式AHI,氧气不和指数 (ODI),睡眠效率,唤醒指数,睡眠问卷 (FOSQ) 的功能结果,坚持或平均SPO2的显著差异.
结论:
- 定位疗法 (PT) 和口服器械疗法 (OAT) 都在治疗阻塞性睡眠呼吸暂停方面有效.
- 口服器械治疗 (OAT) 似乎更有效,在非卧底呼吸暂停-呼吸暂停指数 (AHI) 和改善白天嗜睡 (ESS分数) 中提供更大的降低.
- 定位疗法 (PT) 有效地减少了卧卧姿势睡眠时间.
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