不充分的肠道清洗在西格莫显微镜查中的影响
Kristin Ranheim Randel1, Anna Lisa Schult1,2, Edoardo Botteri1,3
1Section for Colorectal Cancer Screening, Cancer Registry of Norway, NIPH, Oslo, Norway.
不良的肠道清洁显著降低了腺瘤检测率在结直肠癌的西格米多斯科皮查期间. 改善肠道准备对于有效的查至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 预防医学 预防医学
- 在瘤学瘤学.
背景情况:
- 符号显微镜查试验表明结直肠癌 (CRC) 发病率和死亡率降低.
- 然而,低于最佳的肠道清洁质量可能会损害西格莫视镜查的有效性.
- 这项研究研究了肠道准备质量对查疗效的影响.
研究的目的:
- 评估肠道清洁质量的影响在腺瘤检测率 (ADR) 在sigmoidoscopy查.
- 评估肠道清洁质量与随后结肠镜转诊的需要之间的关系.
- 分析肠道清洗评估在内镜医生之间的变化.
主要方法:
- 一项横截面研究包括35710名年龄在50-74岁的人,他们在挪威 (2012-2019) 随机试验中接受了查西格摩陀镜检查.
- 肠道清洁质量被分类为优秀,好,部分差,或差.
- 使用多变量后勤回归模型来评估清洗质量对ADR和结肠镜转诊的影响.
主要成果:
- 在58.6%的参与者中观察到优良的肠道清洁,相应的副作用范围从17.0% (优秀) 到13.0% (差).
- 肠道清洁不良的参与者与肠道清洁良好的人相比,腺瘤检测的几率比率 (0.66) 显著降低.
- 在评估肠道清洁质量时,注意到了大量的内镜间变异性.
结论:
- 不充分的肠道清洁会降低通过降低腺瘤检测率来降低西格莫多斯科比查的有效性.
- 需要一个经过验证的评分尺度和增强的肠道准备协议,以优化作为查工具的西格米多斯科普.
- 标准化的评估和改进的准备对于可靠的西格莫视镜查结果至关重要.
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