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Updated: Jun 24, 2025

Single-Molecule Imaging of Lateral Mobility and Ion Channel Activity in Lipid Bilayers using Total Internal Reflection Fluorescence TIRF Microscopy
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Published on: February 17, 2023

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托宁3是一种缓慢无活化机械敏感通道的孔形成子单元

Sungmin Pak1, Hyunil Ryu2, Sujin Lim3

  • 1Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Korea; College of Pharmacy, Seoul National University, Seoul 08826, Korea.

Cell reports
|June 8, 2024
PubMed
概括

托宁3 (TTN3) 形成了一个独特的机械激活 (MA) 通道,与Piezo1.1分开. 净化后的TTN3蛋白呈现出压力敏感电流和预测的四重体结构,证实其作为毛孔形成子单元的作用.

关键词:
科普:分子生物学 分子生物学

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