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Updated: Jun 24, 2025

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五个与自闭症相关的转录调节器准了与大脑表达的基因相邻的共享位置

Siavash Fazel Darbandi1, Joon-Yong An2, Kenneth Lim1

  • 1Nina Ireland Laboratory of Developmental Neurobiology, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Psychiatry and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94143, USA.

Cell reports
|June 8, 2024
PubMed
概括

五个与自闭症谱系障碍 (ASD) 相关的转录调节器 (TRs) 共享结合部位,影响大脑基因表达. 在小鼠中破坏这些TRs揭示了在人类ASD大脑中观察到的融合神经发育效应.

关键词:
科普:基因组学 基因组学科普:神经科学是什么意思克里斯普里是指克里斯普里.自闭症谱系障碍 自闭症谱系障碍在这种情况下,染色染色素收 收 收 收 收 收基因组学就是基因组学.没有足够的障碍.人类胎儿发育的发展鼠标大脑发育 鼠标大脑发育转录调节器是指转录调节器.

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