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Updated: Jun 24, 2025

Anti-Nuclear Antibody Screening Using HEp-2 Cells
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在ANCA相关的血管炎中,B-淋巴发育和B-细胞成熟的缺陷是长期B-细胞枯竭的基础

Jens Thiel1,2, Franziska M Schmidt3, Raquel Lorenzetti4,2

  • 1Division of Rheumatology and Clinical Immunology, Medical University of Graz, Graz, Austria marta.rizzi@uniklinik-freiburg.de jens.thiel@medunigraz.at.

Annals of the rheumatic diseases
|June 8, 2024
PubMed
概括

利图西马布治疗延长了抗中性细胞质抗体相关血管炎 (AAV) 的B细胞枯竭,原因是骨髓B细胞发育受损和B细胞存活率降低. 这种缺陷被RTX揭露,影响治疗后的B细胞复合.

关键词:
在B-淋巴细胞.这就是Rituximab.血管炎是一种血管炎.

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