超耐力马拉松对心脏功能的影响与心血管生物标志物相关联
Achim Leo Burger1,2, Claudia Wegberger3, Maximilian Tscharre3
13rd Medical Department with Cardiology and Intensive Care Medicine, Clinic Ottakring, Montleartstrasse 37, 1160, Vienna, Austria. achim.leo.burger@gmail.com.
超耐力跑步暂时降低右心室功能,特别是在心脏生物标志物升高的运动员中,如高灵敏心脏Troponin I (hs-cTnI) 和N-终端-pro-大脑-natriuretic-peptide (NT-proBNP). 那些生物标志物水平较低的人心脏功能正常化.
科学领域:
- 心脏病学 心脏病学
- 运动医学 运动医学
- 运动生理学 运动生理学
背景情况:
- 超耐力赛事可能会导致暂时的心脏功能障碍和心脏生物标志物升高.
- 在事件发生后评估双心脏功能对于理解心脏应激至关重要.
研究的目的:
- 为了评估超级马拉松后双心脏功能变化.
- 为了将这些变化与高灵敏性心脏Troponin I (hs-cTnI) 和N-终端-pro-大脑-natriuretic-peptide (NT-proBNP) 的水平相关.
主要方法:
- 十五名超级马拉松跑步者使用跨胸腔心声扫描进行了评估.
- 心脏生物标志物 (hs-cTnI和NT-proBNP) 在赛前,赛后立即和赛后五天被量化.
主要成果:
- 赛后立即和赛后五天,右心室分数面积变化 (FAC) 的显著下降被注意到.
- 运动员在NT-proBNP水平升高后,左心室喷射分数 (LVEF) 立即降低,并在比赛后5天降低.
- 较高的hs-cTnI与赛后FAC降低相关,而LVEF没有受到影响.
结论:
- 长时间运动后心脏功能下降与hs-cTnI和NT-proBNP的升高有关.
- 生物标志物水平低于中位数的运动员在心脏功能上没有显著变化.
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