腹部内感染生存指南:全球手术感染联盟的立场声明
Massimo Sartelli1, Philip Barie2, Vanni Agnoletti3
1Department of Surgery, Macerata Hospital, Via Santa Lucia 2, Macerata, 62100, Italy. massimosartelli@gmail.com.
腹部内感染 (IAI) 需要及时诊断和源控制. 考虑到感染程度和患者因素的个性化管理是IAI治疗最佳结果的关键.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 手术感染 手术感染
背景情况:
- 腹腔内感染 (IAI) 是全球在医院获得的发病率和死亡率的重要原因.
- 有效的管理取决于诊断,源控制和抗微生物治疗.
研究的目的:
- 概述最佳管理腹腔内感染的基本组成部分.
- 强调在治疗复杂的AI时需要个性化的方法.
主要方法:
- 审查当前的临床实践和IAI管理指南.
- 强调整合药理动力学/药理动力学原则和抗菌药物管理.
- 强调持续评估患者的重要性.
主要成果:
- IAI管理的基石包括诊断,源控制,适当的抗菌药物治疗和血液动力学支持.
- 对感染程度,病原体,耐药性风险和宿主因素的个性化评估至关重要.
结论:
- 在复杂的IAI中优化结果需要基于全面的患者和感染评估的量身定制战略.
- 对临床状态和宿主因素的持续重新评估对于有效的IAI管理至关重要.
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