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Updated: Jun 24, 2025

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基于规则的奥米克斯挖矿揭示了抗微生物宏环对抗耐药临床分离物的抗菌性

Zhuo Cheng1,2, Bei-Bei He1, Kangfan Lei3

  • 1Department of Chemistry and The Swire Institute of Marine Science, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

Nature communications
|June 8, 2024
PubMed
概括

我们使用omics挖矿和表达发现了含有aminovinyl-(methyl) cysteine (Avi(Me) Cys的新型抗生素. 马萨提德A对抗性细菌表现出强烈的活性,提供了一个有前途的新抗生素候选者.

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Antimicrobial Proteins01:23

Antimicrobial Proteins

Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
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