在布隆迪COVID-19危机期间与ART中断相关的因素 (EPIC社区研究计划)
Annabelle Niyongabo1,2, Virginie Villes3, Rokhaya Diagne4
1Community-based Research Laboratory, Coalition PLUS, Dakar, Sénégal. aniyongabo@coalitionplus.org.
Scientific reports
|June 8, 2024
概括
COVID-19扰乱了布隆迪的艾滋病毒服务,导致11.7%的艾滋病毒感染者 (PLHIV) 暂停抗逆转录病毒治疗 (ART). 关键因素包括更少的随访和强制披露,而多个月的ART发行和清晰的沟通有助于防止中断.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 艾滋病毒/艾滋病研究研究
背景情况:
- 布隆迪的全国艾滋病毒流行率为0.9%,接近联合国艾滋病规划署2025年目标.
- 危机定期扰乱布隆迪的艾滋病毒卫生服务.
- COVID-19 流行病对持续的艾滋病毒治疗构成了重大威胁.
研究的目的:
- 评估COVID-19危机对布隆迪艾滋病毒感染者 (PLHIV) 中抗逆转录病毒疗法 (ART) 中断的影响.
- 在大流行期间确定与ART中断相关的因素.
主要方法:
- 一个基于社区的项目 (EPIC) 在三座城市调查了317名PLHIV (2021年10月至11月).
- 方便抽样被用来招募参与者.
- 后勤回归模型确定了与ART中断相关的因素.
主要成果:
- 11.7%的受访者 (37/317) 报告了ART的中断.
- 关键人群代表了79.2%的受访者.
- ART中断与更少的艾滋病毒医疗随访 (aOR=7.80) 和强制披露艾滋病毒状况 (aOR=4.10) 相关.
- 多个月的ART处方 (aOR=0.36) 和被认为充足的COVID-19风险沟通 (aOR=0.11) 与更低的中断率有关.
结论:
- 在危机期间,为期数月的ART处方对于维持治疗坚持至关重要.
- 医疗保健提供者加强关于流行病风险的沟通至关重要.
- 自愿披露艾滋病毒状态的支持系统对于防止ART中断至关重要.
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