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与饮食相关的炎症与异位原体指数有积极的关联
Neda Heidarzadeh-Esfahani1,2,3, Salimeh Hajahmadi4, Yahya Pasdar1
1Research Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Scientific reports
|June 8, 2024
概括
饮食炎症指数 (DII) 高,表明一种促炎症饮食,与成年人患有动脉动脉指数和脂质失调的风险增加有关. 这突显了饮食对心血管健康的影响.
科学领域:
- 心血管健康 心血管健康
- 营养流行病学 营养流行病学
- 生物化学 生化学
背景情况:
- 与传统参数相比,非传统的血清脂质比率是血管疾病的优越预测指标.
- 饮食模式显著影响传统和非传统的脂质谱.
- 饮食炎症指数 (DII) 量化了饮食的炎症潜力.
研究的目的:
- 调查DII与各种无氧原体指数之间的关联.
- 检查DII与传统脂质参数 (TG,TC,LDL-c,HDL-c) 之间的关系.
- 评估DII与非传统脂质比率 (AIP,CRI_I,CRI_II,LCI,AC) 的相关性.
主要方法:
- 采用拉凡萨尔非传染性疾病队列数据的横截面观测研究.
- 包括8870名年龄在35-65岁之间的成年人.
- 通过经过验证的食物频率问卷 (FFQ) 评估的饮食炎症指数 (DII).
- 用于分析的多变量线性回归和调整后勤回归模型.
- 共同变量包括年龄,性别,吸烟,酒精,体力活动,血压,禁食血糖,BMI和SES.
主要成果:
- 在多变量调整后,DII最高四分之一的参与者表现出CRI_I,CRI_II,LCI,AC和AIP的风险增加.
- 随着DII四分位数的升高 (Q4:24%的增长),失脂症的风险显著增加.
- 观察到平均DII为-2.5±1.43,患脂质不良的患病率为44%.
结论:
- 饮食相关的炎症,按DII测量,与不良的动脉动脉指数 (CRI-I,CRI-II,LCI,AC,AIP) 有显著的相关性.
- 较高的DII分数与失脂血的可能性增加有关.
- 这些发现强调了抗炎饮食模式对于预防心血管疾病的重要性.
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